BDBM50237117 CHEMBL4078182

SMILES Clc1cccc(NC(=S)Nc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)c1

InChI Key InChIKey=RVUPEWVGGKZLBK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50237117   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50237117(CHEMBL4078182)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human full length N-terminal GST-tagged MNK2 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50237117(CHEMBL4078182)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant full length His-tagged PIM-1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50237117(CHEMBL4078182)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant GST-tagged EGFR (668 to 1210 residues) cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50237117(CHEMBL4078182)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus infected Sf9 insect cells using KHKKLAEGSA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed