BDBM50236918 CHEMBL4081543

SMILES CC(C)[C@H](NC(=O)[C@H](Cc1cscn1)NC(=O)CCc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1

InChI Key InChIKey=JFPVABWUQNRDDL-UHFFFAOYSA-N

Data  12 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50236918   

TargetTransmembrane protease serine 6(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataIC50: 4.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  0.400nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  4nMAssay Description:Inhibition of recombinant human matriptase (596 to 855 residues) expressed in Escherichia coli using Boc-Gln-Ala-ArgAMC as substrate measured for 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  4.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  8.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProthrombin(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  53nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCoagulation factor X(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  323nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProthrombin(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  1.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCoagulation factor X(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  2.32E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFurin(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFurin(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi: >3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed