BDBM50236880 CHEMBL4102311

SMILES [H][C@]12CCC[C@H](N3CCCC3)[C@@]1([H])N(CCN2C(=O)NC(C)C)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=NMNKHDCMGOTGHX-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236880   

TargetKappa-type opioid receptor(Human)
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50236880(CHEMBL4102311)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at recombinant human kappa-type opioid receptor expressed in HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50236880(CHEMBL4102311)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]U-69,593 from kappa-type opioid receptor in guinea pig brain membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details Article
PubMed