BDBM50236855 CHEMBL4102425

SMILES Cc1coc-2c1C(=O)C(=O)c1cc(C)c(C)cc-21

InChI Key InChIKey=VCBCAXHKNPCVCB-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50236855   

TargetNADPH--cytochrome P450 reductase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236855(CHEMBL4102425)
Affinity DataIC50: 3.50E+4nMAssay Description:Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236855(CHEMBL4102425)
Affinity DataIC50: 4.90E+3nMAssay Description:Substrate activity at NQO1 in human H1299 cells assessed as NQO1-mediated two-electron reduction of compound by measuring cell growth inhibition trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236855(CHEMBL4102425)
Affinity DataIC50: 4.80E+3nMAssay Description:Substrate activity at NQO1 in human H522 cells assessed as NQO1-mediated two-electron reduction of compound by measuring cell growth inhibition treat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236855(CHEMBL4102425)
Affinity DataIC50: 9.30E+3nMAssay Description:Substrate activity at NQO1 in human H1650 cells assessed as NQO1-mediated two-electron reduction of compound by measuring cell growth inhibition trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236855(CHEMBL4102425)
Affinity DataIC50: 2.50E+3nMAssay Description:Substrate activity at NQO1 in human HepG2 cells assessed as NQO1-mediated two-electron reduction of compound by measuring cell growth inhibition trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236855(CHEMBL4102425)
Affinity DataIC50: 4.40E+3nMAssay Description:Substrate activity at NQO1 in human HCT116 cells assessed as NQO1-mediated two-electron reduction of compound by measuring cell growth inhibition tre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236855(CHEMBL4102425)
Affinity DataIC50: 3.30E+3nMAssay Description:Substrate activity at NQO1 in human A549 cells assessed as NQO1-mediated two-electron reduction of compound by measuring cell growth inhibition treat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236855(CHEMBL4102425)
Affinity DataIC50: 2.40E+3nMAssay Description:Substrate activity at NQO1 in human MCF7 cells assessed as NQO1-mediated two-electron reduction of compound by measuring cell growth inhibition treat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details Article
PubMed