BDBM50236372 (R)-N-methyl-2-(4-(1-(pyridin-2-ylmethyl)-1H-indazol-5-ylamino)quinazolin-5-yloxy)propanamide::CHEMBL256364

SMILES CNC(=O)[C@@H](C)Oc1cccc2ncnc(Nc3ccc4n(Cc5ccccn5)ncc4c3)c12

InChI Key InChIKey=PMDGVRFVXOHVGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236372   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50236372((R)-N-methyl-2-(4-(1-(pyridin-2-ylmethyl)-1H-indaz...)
Affinity DataIC50: 59nMAssay Description:Inhibition of human erbB2 autophosphorylation in MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed