BDBM50236359 CHEMBL4086085

SMILES CC(=O)c1ccc(CN2CCC3(C2)CCNCC3)cc1

InChI Key InChIKey=LPJNTVSJHIVUNB-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50236359   

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236359(CHEMBL4086085)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using biotinylated H3K4me1 peptide as substrate preincubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2019
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236359(CHEMBL4086085)
Affinity DataIC50: 4.25E+4nMAssay Description:Inhibition of recombinant human MAOB incubated for 15 mins measured after 30 mins by luminescence-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2019
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236359(CHEMBL4086085)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using biotinylated H3K4me1 peptide as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2019
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236359(CHEMBL4086085)
Affinity DataIC50: 8.24E+4nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me1 peptide as substrate preincubated for 15 mins with e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2019
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236359(CHEMBL4086085)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MAOA incubated for 15 mins measured after 30 mins by luminescence-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2019
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236359(CHEMBL4086085)
Affinity DataKi:  4.84E+4nMAssay Description:Competitive inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me1 peptide as substrate preincubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2019
Entry Details Article
PubMed