BDBM50236219 CHEMBL4066091

SMILES C(CCCn1cc(nn1)-c1cccnc1)CCCn1cc(nn1)-c1ccccc1-c1ccccc1

InChI Key InChIKey=GWXTYKSSKFUQSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236219   

TargetNicotinamide phosphoribosyltransferase(Mouse)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236219(CHEMBL4066091)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236219(CHEMBL4066091)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed