BDBM50236118 CHEMBL4065181

SMILES COc1ccc(cc1OC)-c1nn2c(nnc2s1)-c1cccs1

InChI Key InChIKey=YTGYWPTWNBGCLG-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50236118   

TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N-terminal His-tagged dCTPase 1 expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2019
Entry Details Article
PubMed
TargetADP-ribose pyrophosphatase, mitochondrial(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of NUDT9 (unknown origin) by malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2019
Entry Details Article
PubMed
TargetUridine diphosphate glucose pyrophosphatase NUDT14(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human His-tagged NUDT14 expressed in bacterial expression system after 1 hr by malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2019
Entry Details Article
PubMed
TargetBis(5'-nucleosyl)-tetraphosphatase [asymmetrical](Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of NUDT2 (unknown origin) by malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2019
Entry Details Article
PubMed
TargetADP-sugar pyrophosphatase(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human His-tagged NUDT5 expressed in bacterial expression system in presence of ADP after 1 hr by malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2019
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MTH1 using dGTP as substrate after 1 hr by malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2019
Entry Details Article
PubMed
TargetNucleotide triphosphate diphosphatase NUDT15(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human His-tagged NUDT15 expressed in bacterial expression system after 1 hr by malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2019
Entry Details Article
PubMed
TargetInosine triphosphate pyrophosphatase(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human His-tagged ITPase expressed in bacterial expression system after 1 hr by malachite green reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: 20nMAssay Description:Inhibition of human dCTPase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed