BDBM50235985 CHEMBL4092600

SMILES C[C@H](Oc1ccc(Cc2ccc(OCc3coc(n3)-c3ccccc3)cc2)cc1)C(O)=O

InChI Key InChIKey=HMPJUJWJRZHLGY-UHFFFAOYSA-N

Data  2 Kd  2 EC50  2 Koff

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50235985   

TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50235985(CHEMBL4092600)
Affinity DataEC50:  46nMAssay Description:Transactivation of GAL4-fused human PPARalpa LBD expressed in human HepG2 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2019
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50235985(CHEMBL4092600)
Affinity DataKon:  0.0160M-1s-1Assay Description:Binding affinity to PPARalpha (unknown origin) assessed as kinetic dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2019
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50235985(CHEMBL4092600)
Affinity DataKon:  0.0990M-1s-1Assay Description:Binding affinity to PPARgamma (unknown origin) assessed as kinetic dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2019
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50235985(CHEMBL4092600)
Affinity DataEC50:  300nMAssay Description:Transactivation of GAL4-fused human PPARgamma LBD expressed in human HepG2 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2019
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50235985(CHEMBL4092600)
Affinity DataKd:  4.90nMAssay Description:Binding affinity to PPARgamma (unknown origin) assessed as thermodynamic dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2019
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50235985(CHEMBL4092600)
Affinity DataKd:  0.75nMAssay Description:Binding affinity to PPARalpha (unknown origin) assessed as thermodynamic dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2019
Entry Details Article
PubMed