BDBM50235938 17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5r-epoxy-6beta-[(2'-pyridyl)acetamido]morphinan::17-cyclopropylmethyl-3,14-beta-dihydroxy-4,5-alpha-epoxy-6-beta-[(2'-pyridyl)acetamido]morphinan::CHEMBL260528

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)c1ccccn1

InChI Key InChIKey=NHRWXABMYGAAGY-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50235938   

TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50235938(17-cyclopropylmethyl-3,14-beta-dihydroxy-4,5-alpha...)
Affinity DataEC50:  26nMAssay Description:Activity at monocloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50235938(17-cyclopropylmethyl-3,14-beta-dihydroxy-4,5-alpha...)
Affinity DataKi:  5.90nMAssay Description:Activity at monocloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50235938(17-cyclopropylmethyl-3,14-beta-dihydroxy-4,5-alpha...)
Affinity DataKi:  215nMAssay Description:Displacement of [3H]NTI from monocloned delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50235938(17-cyclopropylmethyl-3,14-beta-dihydroxy-4,5-alpha...)
Affinity DataKi:  278nMAssay Description:Displacement of [3H]norBNI from monocloned kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed