BDBM50235799 CHEMBL4096024

SMILES CCC(C)(C)NCC(O)c1cc(OC(=O)N(C)C)cc(OC(=O)N(C)C)c1

InChI Key InChIKey=SYWTZCLVKUGBKA-UHFFFAOYSA-N

Data  4 IC50  2 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50235799   

TargetAcetylcholinesterase(Electric eel)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235799(CHEMBL4096024)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235799(CHEMBL4096024)
Affinity DataKoff:  2.37E+3s-1Assay Description:Irreversible inhibition of equine serum BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235799(CHEMBL4096024)
Affinity DataKoff:  1.00E+5s-1Assay Description:Irreversible inhibition of human plasma BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235799(CHEMBL4096024)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human erythrocytes AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235799(CHEMBL4096024)
Affinity DataIC50: 126nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235799(CHEMBL4096024)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed