BDBM50235350 CHEMBL4094562

SMILES C#Cc1nc(Nc2ccccc2)nc2[nH]cnc12

InChI Key InChIKey=PRKFJWMFXNJCLC-UHFFFAOYSA-N

Data  23 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50235350   

TargetRibosomal protein S6 kinase alpha-1(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of human RSK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 5.54E+4nMAssay Description:Inhibition of human AKT2 by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of human ERK2 by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human GSK-3beta by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human SRC by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human LCK by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 8.68E+4nMAssay Description:Inhibition of human MET by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of human LYN by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of human FYN by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of human ABL by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 4.02E+4nMAssay Description:Inhibition of human CK1d by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of human ERK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human Aurora A by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human ChK2 by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human P70S6K by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human Plk1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 7.67E+4nMAssay Description:Inhibition of human CDK7 by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human ChK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 150nMAssay Description:Inhibition of human NEK2 by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 4.04E+4nMAssay Description:Inhibition of human CDK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek1(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of human NEK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed