BDBM50235339 CHEMBL4073211

SMILES NS(=O)(=O)c1ccc(Nc2ncc3nc[nH]c3n2)cc1

InChI Key InChIKey=ZVHABBMEQZWREZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50235339   

TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235339(CHEMBL4073211)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235339(CHEMBL4073211)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of recombinant human CDK1/Cyclin B expressed in baculovirus infected Sf9 cells using PKTPKKAKKL-NH2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235339(CHEMBL4073211)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal His6-tagged Cdk7/recombinant human full-length Cyclin H expressed in baculovirus infected Sf21...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235339(CHEMBL4073211)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal His6-tagged Cdk9/human full-length Cyclin T expressed in baculovirus infected Sf21 insect cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed