BDBM50235337 CHEMBL4062554

SMILES NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3cc[nH]c3n2)cc1

InChI Key InChIKey=NJZMZGLYZQNCHS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50235337   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235337(CHEMBL4062554)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human CDK1/Cyclin B expressed in baculovirus infected Sf9 cells using PKTPKKAKKL-NH2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235337(CHEMBL4062554)
Affinity DataIC50: 26nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235337(CHEMBL4062554)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human CDK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235337(CHEMBL4062554)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of recombinant human full-length C-terminal His6-tagged Cdk7/recombinant human full-length Cyclin H expressed in baculovirus infected Sf21...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235337(CHEMBL4062554)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human full-length C-terminal His6-tagged Cdk9/human full-length Cyclin T expressed in baculovirus infected Sf21 insect cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed