BDBM50235120 CHEMBL4087670

SMILES [H][C@@]1(CC[C@@H](Cc2ccc(cc2)C(=O)N2CCN(Cc3ncn(CC(F)F)n3)CC2)N1)[C@H](O)c1ccccc1

InChI Key InChIKey=YLRSLIWLHGPCOC-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50235120   

TargetBeta-3 adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50235120(CHEMBL4087670)
Affinity DataEC50:  2.90nMAssay Description:Agonist activity at human beta3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50235120(CHEMBL4087670)
Affinity DataIC50: 2.00E+4nMAssay Description:Activity at human beta2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50235120(CHEMBL4087670)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50235120(CHEMBL4087670)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50235120(CHEMBL4087670)
Affinity DataEC50:  26nMAssay Description:Inhibition of NET (unknown origin) expressed in HEK293 cells assessed as reduction in norepinephrine reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50235120(CHEMBL4087670)
Affinity DataIC50: 2.00E+4nMAssay Description:Activity at human beta1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50235120(CHEMBL4087670)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 by electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed