BDBM50235078 CHEMBL4092912

SMILES [H][C@@]1(CC[C@@H](Cc2ccc(cc2)C(=O)N2CCN(Cc3nnn(CC4CC4)n3)CC2)N1)[C@H](O)c1ccccc1

InChI Key InChIKey=FGGZSKMAUOZIQL-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50235078   

TargetBeta-1 adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50235078(CHEMBL4092912)
Affinity DataIC50: 2.00E+4nMAssay Description:Activity at human beta1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50235078(CHEMBL4092912)
Affinity DataIC50: 3.94E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50235078(CHEMBL4092912)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 by electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50235078(CHEMBL4092912)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50235078(CHEMBL4092912)
Affinity DataEC50:  1.39E+3nMAssay Description:Inhibition of NET (unknown origin) expressed in HEK293 cells assessed as reduction in norepinephrine reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50235078(CHEMBL4092912)
Affinity DataIC50: 2.00E+4nMAssay Description:Activity at human beta2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50235078(CHEMBL4092912)
Affinity DataEC50:  5.20nMAssay Description:Agonist activity at human beta3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details Article
PubMed