BDBM50234863 8-(4-hydroxybutyl)-1-methyl-7-phenyl-1H-imidazo[1,2-a]purine-2,4(3H,8H)-dione::8-(4-hydroxybutyl)-1-methyl-7-phenyl-1H-imidazo[1,2-f]purine-2,4(3H,8H)-dione::CHEMBL271179

SMILES Cn1c2nc3n(CCCCO)c(cn3c2c(=O)[nH]c1=O)-c1ccccc1

InChI Key InChIKey=JOEYVYNGBCYTGH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234863   

TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50234863(8-(4-hydroxybutyl)-1-methyl-7-phenyl-1H-imidazo[1,...)
Affinity DataIC50: 5.68E+3nMAssay Description:Inhibition of EphB4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50234863(8-(4-hydroxybutyl)-1-methyl-7-phenyl-1H-imidazo[1,...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of EphB4 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50234863(8-(4-hydroxybutyl)-1-methyl-7-phenyl-1H-imidazo[1,...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50234863(8-(4-hydroxybutyl)-1-methyl-7-phenyl-1H-imidazo[1,...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of EphB4 by Panvera FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed