BDBM50234769 CHEMBL4095908

SMILES COc1cccc(c1)C1c2ccc3cccnc3c2Oc2nc3CCCCc3c(N)c12

InChI Key InChIKey=VQICOKOVXNVBBA-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234769   

TargetCholinesterase(Horse)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50234769(CHEMBL4095908)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of horse serum BuChE using butyrylthiocholine as substrate pretreated for 10 mins followed by substrate addition measured after 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50234769(CHEMBL4095908)
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50234769(CHEMBL4095908)
Affinity DataIC50: 40nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate pretreated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50234769(CHEMBL4095908)
Affinity DataKi:  870nMAssay Description:Non-competitive inhibition of recombinant human AChE expressed in HEK293 cells using varying levels of acetylthiocholine iodide as substrate pretreat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2019
Entry Details Article
PubMed