BDBM50234645 CHEMBL253865::N-((2S,3S)-4-(3-(2H-tetrazol-5-yl)phenylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-4-oxo-6-((S)-4-phenyloxazolidine-3-carbonyl)-1,4-dihydropyridine-2-carboxamide

SMILES O[C@@H]([C@H](Cc1ccccc1)NC(=O)c1cc(O)cc(n1)C(=O)N1COC[C@@H]1c1ccccc1)C(=O)Nc1cccc(c1)-c1nnn[nH]1

InChI Key InChIKey=NORLMBBEWXGLPH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234645   

TargetBeta-secretase 1(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50234645(N-((2S,3S)-4-(3-(2H-tetrazol-5-yl)phenylamino)-3-h...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50234645(N-((2S,3S)-4-(3-(2H-tetrazol-5-yl)phenylamino)-3-h...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant Arg235 region of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed