BDBM50234631 CHEMBL4078686

SMILES CC[C@H](C)[C@H](NC(=S)Nc1cccc(c1)[N+]([O-])=O)C(=O)N[C@H](Cc1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=IRWODQZCBZBXAS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234631   

TargetProteasome subunit beta type-5(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50234631(CHEMBL4078686)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-AMC as substrate by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2019
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50234631(CHEMBL4078686)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using (Z)-LLE-bNA as substrate by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2019
Entry Details Article
PubMed