BDBM50234596 CHEMBL1884989

SMILES C(c1ccccc1)n1nnc2ccccc12

InChI Key InChIKey=OQVSPZZIBWDHOF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234596   

TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50234596(CHEMBL1884989)
Affinity DataEC50:  3.00E+3nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50234596(CHEMBL1884989)
Affinity DataIC50: 7.25E+4nMAssay Description:Inhibition of platelet NHE1 in human platelet rich plasma assessed as decrease in platelet swelling preincubated for 3 mins followed by sodium propio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details Article
PubMed