BDBM50234567 1,4-dideoxy-1,4-imino-D-ribitol::CHEMBL261634::IMINORIBITOL

SMILES C1[C@@H]([C@@H]([C@H](N1)CO)O)O

InChI Key InChIKey=OQEBIHBLFRADNM-UHFFFAOYSA-N

Data  3 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50234567   

TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50234567(IMINORIBITOL | 1,4-dideoxy-1,4-imino-D-ribitol | C...)
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of rat intestinal sucrase assessed as glucose release by Glucose B-testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50234567(IMINORIBITOL | 1,4-dideoxy-1,4-imino-D-ribitol | C...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of rat intestinal isomaltase assessed as glucose release by Glucose B-testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-mannosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50234567(IMINORIBITOL | 1,4-dideoxy-1,4-imino-D-ribitol | C...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of rat epididymis beta-mannosidase assessed as p-nitrophenol release by spectrophotometricallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-galactosidase(Bovine)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50234567(IMINORIBITOL | 1,4-dideoxy-1,4-imino-D-ribitol | C...)
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as p-nitrophenol release by spectrophotometricallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50234567(IMINORIBITOL | 1,4-dideoxy-1,4-imino-D-ribitol | C...)
Affinity DataKi:  1.26E+3nMAssay Description:Inhibition of human ER alpha mannosidase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIAG-nucleoside hydrolase(Trypanosoma vivax)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50234567(IMINORIBITOL | 1,4-dideoxy-1,4-imino-D-ribitol | C...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibition of Trypanosoma vivax IAG-nucleoside hydrolase expressed in Escherichia coli WK6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Human)
Universidade Do Porto 687

Curated by ChEMBL
LigandPNGBDBM50234567(IMINORIBITOL | 1,4-dideoxy-1,4-imino-D-ribitol | C...)
Affinity DataKi:  1.43E+6nMAssay Description:Inhibition of human golgi alpha mannosidase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed