BDBM50234455 CHEMBL2414438

SMILES NS(=O)(=O)c1ccc(CCN2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1

InChI Key InChIKey=GNOITBWORAUPOH-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50234455   

TargetCarbonic anhydrase 2(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234455(CHEMBL2414438)
Affinity DataKi:  2.90nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234455(CHEMBL2414438)
Affinity DataKi:  3.5nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234455(CHEMBL2414438)
Affinity DataKi:  68nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 10 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50234455(CHEMBL2414438)
Affinity DataKi:  284nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 10 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234455(CHEMBL2414438)
Affinity DataKi:  326nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234455(CHEMBL2414438)
Affinity DataKi:  562nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 10 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50234455(CHEMBL2414438)
Affinity DataKi:  9.23E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 incubated for 10 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2019
Entry Details Article
PubMed