BDBM50234077 CHEMBL4066791

SMILES COc1ccc(cc1OC)C(=O)Nc1ccc(C)c(NC(=O)c2ccc3nc(C)ccc3c2)c1

InChI Key InChIKey=FTGOUPOXQVQHPW-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234077   

TargetPirin(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234077(CHEMBL4066791)
Affinity DataKd: <1.00E+3nMAssay Description:Binding affinity to recombinant human pirin by surface plasma resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2019
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234077(CHEMBL4066791)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2019
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234077(CHEMBL4066791)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2019
Entry Details Article
PubMed
TargetPirin(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234077(CHEMBL4066791)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to recombinant human pirin by surface plasma resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2019
Entry Details Article
PubMed