BDBM50233990 CHEMBL4104957

SMILES c1ccc(cc1)c2cc(ccc2[C@H](C(F)(F)F)Oc3cc(nc(n3)N)N4CCC5(CC4)C[C@H](NC5)C(=O)O)Cl

InChI Key InChIKey=ZNSPHKJFQDEABI-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233990   

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50233990(CHEMBL4104957)
Affinity DataIC50: 33nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTryptophan 5-hydroxylase 2(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50233990(CHEMBL4104957)
Affinity DataIC50: 7nMAssay Description:Inhibition of TPH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed