BDBM50233887 CHEMBL1511860

SMILES C(Sc1nc[nH]n1)c1csc(Nc2ccccc2)n1

InChI Key InChIKey=WLZCMHNSPJKOQN-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50233887   

Target72 kDa type IV collagenase(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of APMA-activated recombinant human MMP-2 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of APMA-activated recombinant human MMP-8 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
TargetStromelysin-2(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of APMA-activated recombinant human MMP-3 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
TargetMatrilysin(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of APMA-activated recombinant human MMP-7 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of APMA-activated recombinant human MMP-9 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of APMA-activated recombinant human GST-tagged MMP-14 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of APMA-activated recombinant human MMP-1 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233887(CHEMBL1511860)
Affinity DataIC50: 1.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed