BDBM50233708 CHEMBL253864::N-(2-(piperidin-1-yl)phenyl)isoxazole-5-carboxamide

SMILES O=C(Nc1ccccc1N1CCCCC1)c1ccno1

InChI Key InChIKey=WXDDTTSLPVVQOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233708   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50233708(N-(2-(piperidin-1-yl)phenyl)isoxazole-5-carboxamid...)
Affinity DataIC50: 400nMAssay Description:Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50233708(N-(2-(piperidin-1-yl)phenyl)isoxazole-5-carboxamid...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed