BDBM50233703 5-cyano-N-(5-(4-methylpiperazin-1-yl)-3-(4-methylpiperidin-1-yl)pyridin-2-yl)furan-2-carboxamide::CHEMBL251842

SMILES CC1CCN(CC1)c1cc(cnc1NC(=O)c1ccc(o1)C#N)N1CCN(C)CC1

InChI Key InChIKey=LLMXYGNWHKKVNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233703   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50233703(5-cyano-N-(5-(4-methylpiperazin-1-yl)-3-(4-methylp...)
Affinity DataIC50: 720nMAssay Description:Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed