BDBM50233521 CHEMBL3975922

SMILES Cc1c(CC(O)=O)c2cccnc2n1Cc1ccc(cc1C)S(C)(=O)=O

InChI Key InChIKey=QEIQIUMAMIISFB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50233521   

TargetProstaglandin D2 receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50233521(CHEMBL3975922)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at DP2 receptor in human isolated eosinophils assessed as inhibition of DK-PGD2-induced shape change preincubated for 5 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50233521(CHEMBL3975922)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at DP2 receptor in human whole assessed as inhibition of DK-PGD2-induced eosinophils shape change preincubated for 5 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50233521(CHEMBL3975922)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]PGD2 from human DP2 receptor expressed in CHO cell membranes after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details Article
PubMed