BDBM50233289 CHEMBL1241726

SMILES Clc1ccc2c(NCCCN3CCOCC3)ccnc2c1

InChI Key InChIKey=YXFRGFRPDJRMHG-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50233289   

TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Minas Gerais

Curated by ChEMBL
LigandPNGBDBM50233289(CHEMBL1241726)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-phe-Arg-amidomethylcoumarin as substrate by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2019
Entry Details Article
PubMed
TargetFermitin family homolog 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50233289(CHEMBL1241726)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of His6-tagged KIND1 (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence polarization methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetFermitin family homolog 2(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50233289(CHEMBL1241726)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of His6-tagged KIND2 (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence polarization methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Minas Gerais

Curated by ChEMBL
LigandPNGBDBM50233289(CHEMBL1241726)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Minas Gerais

Curated by ChEMBL
LigandPNGBDBM50233289(CHEMBL1241726)
Affinity DataKi:  1.21E+4nMAssay Description:Competitive inhibition of recombinant Trypanosoma cruzi cruzain in presence of varying levels of Z-phe-Arg-amidomethylcoumarin substrate by Lineweave...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2019
Entry Details Article
PubMed