BDBM50232832 CHEMBL4090527

SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1ccc2nc(Nc3ccccc3NC(=O)C=C)ncc2c1

InChI Key InChIKey=NFYOODCIQOKJEY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50232832   

TargetFibroblast growth factor receptor 4(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50232832(CHEMBL4090527)
Affinity DataIC50: 3nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR4 cytoplasmic domain (460 to 802 end residues) expressed in baculovirus expression system using CSKtide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50232832(CHEMBL4090527)
Affinity DataIC50: 591nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR1 cytoplasmic domain (398 to 822 residues) expressed in baculovirus expression system using CSKtide as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50232832(CHEMBL4090527)
Affinity DataIC50: 493nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR2 cytoplasmic domain (399 to 821 end residues) expressed in baculovirus expression system using CSKtide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50232832(CHEMBL4090527)
Affinity DataIC50: 150nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR3 cytoplasmic domain (436 to 806 end residues) expressed in baculovirus expression system using CSKtide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed