BDBM50232712 CHEMBL4092498::US11046670, Compound 28

SMILES [H][C@]12C[C@@]([H])(N(CC1)C(=O)OCc1ccccc1)c1cc(ccc21)N1CCN(CC=C)CC1

InChI Key

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50232712   

TargetSigma intracellular receptor 2(Human)
University Of Texas

US Patent
LigandPNGBDBM50232712(CHEMBL4092498 | US11046670, Compound 28)
Affinity DataKi:  34nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Rat)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50232712(CHEMBL4092498 | US11046670, Compound 28)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells in presence of (+)-pentazocine by PDSP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University Of Texas

US Patent
LigandPNGBDBM50232712(CHEMBL4092498 | US11046670, Compound 28)
Affinity DataKi:  589nMAssay Description:Receptor binding assays were performed by the Psychoactive Drug Screening Program (PDSP) at Chapel Hill, N.C. The assay protocol book can be accessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50232712(CHEMBL4092498 | US11046670, Compound 28)
Affinity DataKi:  931nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed