BDBM50232677 CHEMBL4074528

SMILES COc1ccc(C[C@H](NC(=O)c2cccc(=O)[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=SSVSAZRGBWOUOO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50232677   

TargetProteasome subunit beta type-10(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232677(CHEMBL4074528)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of MECL1 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232677(CHEMBL4074528)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of proteasome beta5 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232677(CHEMBL4074528)
Affinity DataIC50: 4.81E+3nMAssay Description:Inhibition of LMP7 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232677(CHEMBL4074528)
Affinity DataIC50: 140nMAssay Description:Inhibition of LMP2 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232677(CHEMBL4074528)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of proteasome beta2 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232677(CHEMBL4074528)
Affinity DataIC50: 9.11E+4nMAssay Description:Inhibition of proteasome beta1 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed