BDBM50232561 5-((1-(2-fluorophenylsulfonyl)piperidin-4-yl)methoxy)quinazoline-2,4-diamine::CHEMBL251434

SMILES Nc1nc(N)c2c(OCC3CCN(CC3)S(=O)(=O)c3ccccc3F)cccc2n1

InChI Key InChIKey=RJDJVSWYXOUREL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232561   

TargetDihydrofolate reductase(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50232561(5-((1-(2-fluorophenylsulfonyl)piperidin-4-yl)metho...)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed