BDBM50232550 CHEMBL4062620

SMILES C[C@H](NC(=O)c1cc(Cl)cnc1Oc1cccc(Cl)c1)c1ccc(cc1)C(O)=O

InChI Key InChIKey=PAASJZUYDQEILO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232550   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232550(CHEMBL4062620)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232550(CHEMBL4062620)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed