BDBM50232548 CHEMBL4094572

SMILES C[C@H](NC(=O)c1cc(Cl)cnc1Oc1cccc(c1)C#N)c1ccc(cc1)C(O)=O

InChI Key InChIKey=QEJPFCHVBBYBQL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50232548   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232548(CHEMBL4094572)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232548(CHEMBL4094572)
Affinity DataIC50: 3.32E+3nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232548(CHEMBL4094572)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232548(CHEMBL4094572)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232548(CHEMBL4094572)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human EP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed