BDBM50232546 CHEMBL4103046

SMILES OC(=O)c1ccc(CNC(=O)c2cc(F)cnc2Oc2ccc(F)cc2)cc1

InChI Key InChIKey=MKVAIHBXTDOGGX-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50232546   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232546(CHEMBL4103046)
Affinity DataIC50: 104nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232546(CHEMBL4103046)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232546(CHEMBL4103046)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232546(CHEMBL4103046)
Affinity DataIC50: 575nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232546(CHEMBL4103046)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human EP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232546(CHEMBL4103046)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed