BDBM50232519 (2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trifluoromethyl)-5,6-dihydro [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-oxo-1-(2,4,5-trifluorophenyl)butan-2-amine hydrochloride::CHEMBL536312

SMILES N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=LZHNXTZICCTVCO-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50232519   

TargetProlyl endopeptidase FAP(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetXaa-Pro aminopeptidase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of amino peptidase PMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetXaa-Pro aminopeptidase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of amino peptidase PMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232519((2R)-4-[8-[3,5-bis(trifluoromethyl)benzyl]-3-(trif...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed