BDBM50232478 CHEMBL403233

SMILES O[C@@]12CC\C=C/CCCCN3CC[C@@H](C(=C1)c1nccc4c5ccccc5[nH]c14)[C@]1(C[C@@H]4\C=C/CCCCN4[C@@H]21)C3

InChI Key InChIKey=FUCSLKWLLSEMDQ-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50232478   

TargetGlycogen synthase kinase-3 beta(Human)
University of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50232478(CHEMBL403233)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of recombinant GSK3-beta Z'-LYTE kinase assay kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50232478(CHEMBL403233)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human recombinant GSKbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50232478(CHEMBL403233)
Affinity DataIC50: 4.80E+3nMAssay Description:Non-competitive inhibition of human microsomal ACAT2 overexpressed in CHO cells using [14C]oleoyl-CoA as substrate assessed as formation of cholester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50232478(CHEMBL403233)
Affinity DataIC50: 6.20E+3nMAssay Description:Non-competitive inhibition of human microsomal ACAT1 overexpressed in CHO cells using [14C]oleoyl-CoA as substrate assessed as formation of cholester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50232478(CHEMBL403233)
Affinity DataIC50: 6.40E+3nMAssay Description:Non-competitive inhibition of microsomal ACAT in human MDM using [14C]oleoyl-CoA as substrate assessed as formation of cholesteryl [14C]-oleate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50232478(CHEMBL403233)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of recombinant GSK3-beta by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50232478(CHEMBL403233)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50232478(CHEMBL403233)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50232478(CHEMBL403233)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50232478(CHEMBL403233)
Affinity DataIC50: 1.02E+4nMAssay Description:Non-ATP competitive inhibition of GSK3betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50232478(CHEMBL403233)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant CDK5/p35More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50232478(CHEMBL403233)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of Staphylococcus aureus ATCC 6538p SortA expressed in Escherichia coli using Dabcyl-QALPETGEE-Edans as substrate after 1 hr by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2020
Entry Details Article
PubMed