BDBM50232473 CHEMBL4087627

SMILES NC(=S)N\N=C(/c1cccc(O)c1)c1cc(Br)cc(Br)c1

InChI Key InChIKey=RISJFQWXMQSRIY-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232473   

TargetProcathepsin L(Human)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50232473(CHEMBL4087627)
Affinity DataIC50: 202nMAssay Description:Inhibition of human liver cathepsin-L using Z-FR-AMC as substrate preincubated for 5 mins followed by substrate addition measured at 15 sec interval ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details Article
PubMed
TargetCathepsin B(Human)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50232473(CHEMBL4087627)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human liver cathepsin-B using Z-RR-AMC as substrate preincubated for 5 mins followed by substrate addition measured for 5 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50232473(CHEMBL4087627)
Affinity DataKi:  8.40nMAssay Description:Covalent/reversible inhibition of human liver cathepsin-L using Z-FR-AMC as substrate preincubated for 5 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details Article
PubMed