BDBM50232432 CHEMBL4065659

SMILES C[C@H]1CNC[C@@H](C)N1c1cccc(c1)-c1cc(-c2ccnn2C2CCOCC2)c2c(N)ncnn12

InChI Key InChIKey=IKMRFDFNQYTUNP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232432   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50232432(CHEMBL4065659)Copy SMILESCopy InChI

Affinity DataIC50: 11nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/14/2019
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50232432(CHEMBL4065659)Copy SMILESCopy InChI

Affinity DataIC50: 314nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/14/2019
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL