BDBM50232424 CHEMBL4097123

SMILES COc1cc2cc(Oc3ccc(NC(=O)Nc4cc(cc(c4)C(F)(F)F)C(F)(F)F)cc3)c(C)nc2cc1OC

InChI Key InChIKey=QYLPLBYYWGUQPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232424   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50232424(CHEMBL4097123)
Affinity DataIC50: 370nMAssay Description:Inhibition of human c-RAF using MEK1 as substrate in presence of [33P]ATP by Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50232424(CHEMBL4097123)
Affinity DataIC50: 370nMAssay Description:Inhibition of c-Raf (unknown origin) in presence of ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed