BDBM50232240 4-(2-chlorophenyl)-8-(4-(dimethylamino)butyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL401746

SMILES CN(C)CCCCc1cc2[nH]c3cc(c4C(=O)NC(=O)c4c3c2cc1O)-c1ccccc1Cl

InChI Key InChIKey=CWXCDIQIRXEVOH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50232240   

TargetSerine/threonine-protein kinase Chk1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50232240(4-(2-chlorophenyl)-8-(4-(dimethylamino)butyl)-9-hy...)
Affinity DataIC50: 55nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50232240(4-(2-chlorophenyl)-8-(4-(dimethylamino)butyl)-9-hy...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human Cdc2 kinase PY15 phosphorylation in HT29 cells by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50232240(4-(2-chlorophenyl)-8-(4-(dimethylamino)butyl)-9-hy...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50232240(4-(2-chlorophenyl)-8-(4-(dimethylamino)butyl)-9-hy...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed