BDBM50232040 CHEMBL4087757

SMILES CNc1cc(Oc2ccc(NC(=S)Nc3cccc(c3)C(F)(F)F)cc2F)ncn1

InChI Key InChIKey=DGVQBEQHOGBTQQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232040   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50232040(CHEMBL4087757)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged RAF1 (306-end residues) expressed in baculovirus infected Sf21 cells in presence of [gamma33P]A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50232040(CHEMBL4087757)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged ERK1 expressed in Escherichia coli in presence of [gamma33P]ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details Article
PubMed