BDBM50231825 CHEMBL4090123::US11725000, Compound 26

SMILES FC(F)(F)c1cc(nc(n1)S(=O)(=O)CCc1ccccc1)-c1cccs1

InChI Key InChIKey=CUFXDPKWUBCCPK-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50231825   

LigandPNGBDBM50231825(CHEMBL4090123 | US11725000, Compound 26)
Affinity DataEC50:  1.59E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50231825(CHEMBL4090123 | US11725000, Compound 26)
Affinity DataEC50:  94nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
Go to US Patent

LigandPNGBDBM50231825(CHEMBL4090123 | US11725000, Compound 26)
Affinity DataEC50:  5.50E+3nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
Go to US Patent