BDBM50231767 5-(4-cyanophenyl)-N-(3-methylphenyl)furan-2-carboxamide::CHEMBL401258

SMILES Cc1cccc(NC(=O)c2ccc(o2)-c2ccc(cc2)C#N)c1

InChI Key InChIKey=WKHNOPNLWLSUBU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50231767   

TargetTranslocator protein(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50231767(5-(4-cyanophenyl)-N-(3-methylphenyl)furan-2-carbox...)
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to peripheral benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50231767(5-(4-cyanophenyl)-N-(3-methylphenyl)furan-2-carbox...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant Nav 1.8 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50231767(5-(4-cyanophenyl)-N-(3-methylphenyl)furan-2-carbox...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by isotope efflux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50231767(5-(4-cyanophenyl)-N-(3-methylphenyl)furan-2-carbox...)
Affinity DataIC50: 480nMAssay Description:Inhibition of mouse recombinant Nav 1.8 channel expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50231767(5-(4-cyanophenyl)-N-(3-methylphenyl)furan-2-carbox...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human Nav1.5 channel at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed