BDBM50231676 3-(ethylamino)-N-((2S,3R)-3-hydroxy-4-(1-(3-methoxyphenyl)cyclohexylamino)-1-phenylbutan-2-yl)-5-(2-oxopyrrolidin-1-yl)benzamide::CHEMBL403427

SMILES CCNc1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC1(CCCCC1)c1cccc(OC)c1)N1CCCC1=O

InChI Key InChIKey=WSYWLGZDHCWXRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50231676   

TargetBeta-secretase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231676(3-(ethylamino)-N-((2S,3R)-3-hydroxy-4-(1-(3-methox...)
Affinity DataIC50: 14nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231676(3-(ethylamino)-N-((2S,3R)-3-hydroxy-4-(1-(3-methox...)
Affinity DataIC50: 370nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231676(3-(ethylamino)-N-((2S,3R)-3-hydroxy-4-(1-(3-methox...)
Affinity DataIC50: 380nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed