BDBM50231507 (2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic acid::(S)-2-{3-[(4-adamantan-1-yl-benzoylamino)-methyl]-4-propoxy-benzyl}-butyric acid::CHEMBL402840

SMILES CCCOc1ccc(C[C@H](CC)C(O)=O)cc1CNC(=O)c1ccc(cc1)C12CC3CC(CC(C3)C1)C2

InChI Key

Data  14 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50231507   

TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  58nMAssay Description:Agonist activity at PPARalpha transfected in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at PPARdelta transfected in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  43nMAssay Description:Agonist activity at PPARgamma transfected in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  41nMAssay Description:Transactivation of human PPARgamma expressed in human HEK293 cells after 16 to 20 hrs by dual luciferase beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  130nMAssay Description:Transactivation of human PPARdelta expressed in human HEK293 cells after 16 to 20 hrs by dual luciferase beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  54nMAssay Description:Transactivation of human PPARalpha expressed in human HEK293 cells after 16 to 20 hrs by dual luciferase beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  61nMAssay Description:Agonist activity at human recombinant PPARalpha in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human recombinant PPARalpha in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human recombinant PPARdelta in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human recombinant PPARdelta in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human recombinant PPARgamma in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human recombinant PPARgamma in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  54nMAssay Description:Transactivation of Gal4-fused human PPARalpha expressed in HEK293 cells after 16 to 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50231507((2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3...)
Affinity DataEC50:  41nMAssay Description:Transactivation of Gal4-fused human PPARgamma expressed in HEK293 cells after 16 to 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed