BDBM50231454 CHEMBL252816::N-(6-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-2,3-dihydro-1H-inden-1-yl)-2,2,2-trifluoroacetamide

SMILES FC(F)(F)C(=O)NC1CCc2ccc(CCN3CCN(CC3)c3nsc4ccccc34)cc12

InChI Key InChIKey=ZUJPXZIUFHGAJI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50231454   

TargetAlpha-1A adrenergic receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50231454(N-(6-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl...)
Affinity DataKi:  1.92nMAssay Description:Displacement of [3H]prazosin from rat adrenergic alpha1A receptor expressed in fibroblast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50231454(N-(6-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]8OHDPAT from human 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50231454(N-(6-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]spiperone from human D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50231454(N-(6-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed