BDBM50231057 CHEMBL253843::N-(2-(7-hydroxy-3,4-dihydroquinolin-1(2H)-yl)ethyl)-4-(trifluoromethoxy)benzamide

SMILES Oc1ccc2CCCN(CCNC(=O)c3ccc(OC(F)(F)F)cc3)c2c1

InChI Key InChIKey=MKVINKFSJSMUIZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231057   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50231057(N-(2-(7-hydroxy-3,4-dihydroquinolin-1(2H)-yl)ethyl...)Copy SMILESCopy InChI

Affinity DataIC50: 960nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced calcium influx in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/11/2009
Entry Details Article
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